Increased Microvascularization and Vessel Permeability Associate With Active Inflammation in Human Atheromata | Zendy

Viviany R. Taqueti | Zendy; Marcelo F. Di Carli | Zendy; Michael JeroschHerold | Zendy; Galina K. Sukhova | Zendy; Venkatesh L. Murthy | Zendy; Eduardo J. Folco | Zendy; Raymond Y. Kwong | Zendy; C. Keith Ozaki | Zendy; Michael Belkin | Zendy; Matthias Nahrendorf | Zendy; Ralph Weissleder | Zendy; Peter Libby | Zendy

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Increased Microvascularization and Vessel Permeability Associate With Active Inflammation in Human Atheromata

Author(s) -

Viviany R. Taqueti,

Marcelo F. Di Carli,

Michael JeroschHerold,

Galina K. Sukhova,

Venkatesh L. Murthy,

Eduardo J. Folco,

Raymond Y. Kwong,

C. Keith Ozaki,

Michael Belkin,

Matthias Nahrendorf,

Ralph Weissleder,

Peter Libby

Publication year - 2014

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.114.002113

Subject(s) - medicine , inflammation , permeability (electromagnetism) , pathology , genetics , membrane , biology

Studies have shown the feasibility of imaging plaques with 2-deoxy-2-[(18)F]fluoroglucose (FDG) positron emission tomography and dynamic contrast-enhanced magnetic resonance imaging with inconsistent results. We sought to investigate the relationship between markers of inflammatory activation, plaque microvascularization, and vessel wall permeability in subjects with carotid plaques using a multimodality approach combining FDG positron emission tomography, dynamic contrast-enhanced magnetic resonance imaging, and histopathology.

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