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Endothelial Shear Stress and Coronary Plaque Characteristics in Humans
Author(s) -
Rocco Vergallo,
Michail I. Papafaklis,
Taishi Yonetsu,
Christos V. Bourantas,
Ioannis Andreou,
Zhao Wang,
James G. Fujimoto,
Iris McNulty,
Hang Lee,
Luigi M. Biasucci,
Filippo Crea,
Charles L. Feldman,
Lampros K. Michalis,
Peter H. Stone,
Ik–Kyung Jang
Publication year - 2014
Publication title -
circulation cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.584
H-Index - 99
eISSN - 1942-0080
pISSN - 1941-9651
DOI - 10.1161/circimaging.114.001932
Subject(s) - shear stress , cardiology , medicine , materials science , composite material
Despite the exposure of the entire vasculature to the atherogenic effects of systemic risk factors, atherosclerotic plaques preferentially develop at sites with disturbed flow. This study aimed at exploring in vivo the relationship between local endothelial shear stress (ESS) and coronary plaque characteristics in humans using computational fluid dynamics and frequency-domain optical coherence tomography.

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