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Biomarkers improve cardiovascular disease (CVD) risk prediction, but their comparative effectiveness in clinical practice is not known. We sought to compare the use, spending, and clinical outcomes in asymptomatic Medicare beneficiaries evaluated for CVD with coronary artery calcium (CAC) or other cardiovascular risk markers.

Outcomes After Coronary Artery Calcium and Other Cardiovascular Biomarker Testing Among Asymptomatic Medicare Beneficiaries