Coronary Plaque Structural Stress Is Associated With Plaque Composition and Subtype and Higher in Acute Coronary Syndrome | Zendy

Zhongzhao Teng | Zendy; Adam J. Brown | Zendy; Patrick A. Calvert | Zendy; Richard A. Parker | Zendy; Daniel R. Obaid | Zendy; Yuan Huang | Zendy; Stephen P. Hoole | Zendy; Nick E.J. West | Zendy; Jonathan H. Gillard | Zendy; Martin R. Bennett | Zendy

Open Access

Coronary Plaque Structural Stress Is Associated With Plaque Composition and Subtype and Higher in Acute Coronary Syndrome

Author(s) -

Zhongzhao Teng,

Adam J. Brown,

Patrick A. Calvert,

Richard A. Parker,

Daniel R. Obaid,

Yuan Huang,

Stephen P. Hoole,

Nick E.J. West,

Jonathan H. Gillard,

Martin R. Bennett

Publication year - 2014

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.113.001526

Subject(s) - medicine , intravascular ultrasound , fibrous cap , acute coronary syndrome , vulnerable plaque , cardiology , calcification , pathology , myocardial infarction

Atherosclerotic plaques underlying most myocardial infarctions have thin fibrous caps and large necrotic cores; however, these features alone do not reliably identify plaques that rupture. Rupture occurs when plaque structural stress (PSS) exceeds mechanical strength. We examined whether PSS could be calculated in vivo based on virtual histology (VH) intravascular ultrasound and whether PSS varied according to plaque composition, subtype, or clinical presentation.

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