18F-Sodium Fluoride Uptake Is a Marker of Active Calcification and Disease Progression in Patients With Aortic Stenosis | Zendy

Marc R. Dweck | Zendy; William Jenkins | Zendy; Alex Vesey | Zendy; Mark A.H. Pringle | Zendy; Calvin Chin | Zendy; Tamir Malley | Zendy; William J.A. Cowie | Zendy; Vasiliki Tsampasian | Zendy; Hamish Richardson | Zendy; Alison Fletcher | Zendy; William Wallace | Zendy; Renzo Pessotto | Zendy; Edwin J.R. van Beek | Zendy; Nicholas A. Boon | Zendy; James H.F. Rudd | Zendy; David E. Newby | Zendy

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18F-Sodium Fluoride Uptake Is a Marker of Active Calcification and Disease Progression in Patients With Aortic Stenosis

Author(s) -

Marc R. Dweck,

William Jenkins,

Alex Vesey,

Mark A.H. Pringle,

Calvin Chin,

Tamir Malley,

William J.A. Cowie,

Vasiliki Tsampasian,

Hamish Richardson,

Alison Fletcher,

William Wallace,

Renzo Pessotto,

Edwin J.R. van Beek,

Nicholas A. Boon,

James H.F. Rudd,

David E. Newby

Publication year - 2014

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.113.001508

Subject(s) - medicine , calcification , sodium fluoride , osteocalcin , stenosis , alkaline phosphatase , pathology , fluoride , chemistry , inorganic chemistry , biochemistry , enzyme

18F-Sodium fluoride (18F-NaF) and 18F-fluorodeoxyglucose (18F-FDG) are promising novel biomarkers of disease activity in aortic stenosis. We compared 18F-NaF and 18F-FDG uptake with histological characterization of the aortic valve and assessed whether they predicted disease progression.

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