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We appreciate the insightful comments by Drs Jenni and Martin regarding our recent publication.1 We agree with them that the determination of serial gradients using conventional Doppler data is problematic. The derivation used for Figure 3 results in the generation of negative gradients, which are nonphysiological, supporting the conclusions that we and Drs Jenni and Martin have presented.Drs Jenni and Martin correctly pointed out that the velocity V2 in …

Response to Letter Regarding Article, “Limitations of Doppler Echocardiography in the Evaluation of Serial Stenoses”