Intraperitoneal Injection Improves the Uptake of Nanoparticle-Labeled High-Density Lipoprotein to Atherosclerotic Plaques Compared With Intravenous Injection | Zendy

Caroline Jung | Zendy; Michael G. Kaul | Zendy; Oliver T. Bruns | Zendy; Tanja Dučić | Zendy; Barbara Freund | Zendy; Markus Heine | Zendy; Rudolph Reimer | Zendy; Alke Meents | Zendy; Sunhild C. Salmen | Zendy; Horst Weller | Zendy; Peter Brønnum Nielsen | Zendy; Gerhard Adam | Zendy; Jörg Heeren | Zendy; Harald Ittrich | Zendy

Open Access

Intraperitoneal Injection Improves the Uptake of Nanoparticle-Labeled High-Density Lipoprotein to Atherosclerotic Plaques Compared With Intravenous Injection

Author(s) -

Caroline Jung,

Michael G. Kaul,

Oliver T. Bruns,

Tanja Dučić,

Barbara Freund,

Markus Heine,

Rudolph Reimer,

Alke Meents,

Sunhild C. Salmen,

Horst Weller,

Peter Brønnum Nielsen,

Gerhard Adam,

Jörg Heeren,

Harald Ittrich

Publication year - 2013

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.113.000607

Subject(s) - ex vivo , in vivo , biodistribution , intraperitoneal injection , fluorescence microscope , pathology , fluorescence lifetime imaging microscopy , preclinical imaging , confocal microscopy , medicine , chemistry , nuclear medicine , fluorescence , pharmacology , biology , physics , microbiology and biotechnology , quantum mechanics

The aim of this study was to assess whether high-density lipoprotein (HDL) labeled with superparamagnetic iron oxide nanoparticles (SPIOs) and quantum dots was able to detect atherosclerotic lesions in mice after intravenous and intraperitoneal injection by multimodal imaging.

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