T 1 Mapping With Cardiovascular MRI Is Highly Sensitive for Fabry Disease Independent of Hypertrophy and Sex | Zendy

Richard B. Thompson | Zendy; Kelvin Chow | Zendy; Anzalee Khan | Zendy; Alicia Chan | Zendy; Miriam Shanks | Zendy; D. Ian Paterson | Zendy; Gavin Y. Oudit | Zendy

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T ₁ Mapping With Cardiovascular MRI Is Highly Sensitive for Fabry Disease Independent of Hypertrophy and Sex

Author(s) -

Richard B. Thompson,

Kelvin Chow,

Anzalee Khan,

Alicia Chan,

Miriam Shanks,

D. Ian Paterson,

Gavin Y. Oudit

Publication year - 2013

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.113.000482

Subject(s) - muscle hypertrophy , cardiology , medicine , ejection fraction , concentric hypertrophy , fabry disease , left ventricular hypertrophy , ventricular remodeling , extracellular , extracellular fluid , stroke volume , heart failure , disease , chemistry , blood pressure , biochemistry

Fabry disease (FD) is an X-linked disorder of lysosomal metabolism affecting multiple organs with cardiac disease being the leading cause of death. Current imaging evaluations of the heart are suboptimal. The goals of the current study are to evaluate the potential of quantitative T₁ mapping with cardiovascular MRI as a disease-specific imaging biomarker.

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