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Nanoparticle PET-CT Detects Rejection and Immunomodulation in Cardiac Allografts
Author(s) -
Takuya Ueno,
Partha Dutta,
Edmund J. Keliher,
Florian Leuschner,
Maulik D. Majmudar,
Brett Marinelli,
Yoshiko Iwamoto,
JoseLuiz Figueiredo,
Thomas Christen,
Filip K. Świrski,
Peter Libby,
Ralph Weissleder,
Matthias Nahrendorf
Publication year - 2013
Publication title -
circulation cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.584
H-Index - 99
eISSN - 1942-0080
pISSN - 1941-9651
DOI - 10.1161/circimaging.113.000481
Subject(s) - isograft , transplantation , medicine , positron emission tomography , angiotensin converting enzyme , flow cytometry , myeloid , immune system , pathology , nuclear medicine , immunology , blood pressure
Macrophages predominate among the inflammatory cells in rejecting allografts. These innate immune cells, in addition to allospecific T cells, can damage cardiomyocytes directly.

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