Preclinical Evaluation of Biopolymer-Delivered Circulating Angiogenic Cells in a Swine Model of Hibernating Myocardium | Zendy

Céline Giordano | Zendy; Stephanie Thorn | Zendy; Jennifer M. Renaud | Zendy; Talal AlAtassi | Zendy; Munir Boodhwani | Zendy; Ran Klein | Zendy; Drew Kuraitis | Zendy; Girish Dwivedi | Zendy; Pingchuan Zhang | Zendy; Jean N. DaSilva | Zendy; Kathryn J. Ascah | Zendy; Robert A. deKemp | Zendy; Erik J. Suuronen | Zendy; Rob Beanlands | Zendy; Marc Ruel | Zendy

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Preclinical Evaluation of Biopolymer-Delivered Circulating Angiogenic Cells in a Swine Model of Hibernating Myocardium

Author(s) -

Céline Giordano,

Stephanie Thorn,

Jennifer M. Renaud,

Talal AlAtassi,

Munir Boodhwani,

Ran Klein,

Drew Kuraitis,

Girish Dwivedi,

Pingchuan Zhang,

Jean N. DaSilva,

Kathryn J. Ascah,

Robert A. deKemp,

Erik J. Suuronen,

Rob Beanlands,

Marc Ruel

Publication year - 2013

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.113.000185

Subject(s) - hibernating myocardium , medicine , cardiology , revascularization , coronary artery disease , context (archaeology) , perfusion , blood flow , positron emission tomography , coronary circulation , hibernation (computing) , circumflex , ejection fraction , myocardial infarction , angiogenesis , artery , nuclear medicine , heart failure , biology , paleontology , state (computer science) , algorithm , computer science

Vasculogenic cell-based therapy combined with tissue engineering is a promising revascularization approach targeted at patients with advanced coronary artery disease, many of whom exhibit myocardial hibernation. However, to date, no experimental data have been available in this context; we therefore examined the biopolymer-supported delivery of circulating angiogenic cells using a clinically relevant swine model of hibernating myocardium.

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