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Effects of the Tumor Necrosis Factor-α Antagonist Adalimumab on Arterial Inflammation Assessed by Positron Emission Tomography in Patients With Psoriasis
Author(s) -
Robert Bissonnette,
JeanClaude Tardif,
François Harel,
Joséphine Pressacco,
Chantal Bolduc,
MarieClaude Guertin
Publication year - 2012
Publication title -
circulation cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.584
H-Index - 99
eISSN - 1942-0080
pISSN - 1941-9651
DOI - 10.1161/circimaging.112.975730
Subject(s) - medicine , adalimumab , psoriasis , positron emission tomography , clinical endpoint , cardiology , randomized controlled trial , nuclear medicine , tumor necrosis factor alpha , dermatology
Psoriasis is a chronic inflammatory disease associated with increased risks of myocardial infarction and stroke. Systemic treatments for moderate to severe psoriasis can reduce skin and joint inflammation; however, their effects on vascular inflammation are unknown.

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