Assessment of Echocardiography and Biomarkers for the Extended Prediction of Cardiotoxicity in Patients Treated With Anthracyclines, Taxanes, and Trastuzumab | Zendy

Heloisa Sawaya | Zendy; Igal A. Sebag | Zendy; Juan Carlos Plana | Zendy; James L. Januzzi | Zendy; Bonnie Ky | Zendy; Timothy C. Tan | Zendy; Victor Cohen | Zendy; José Banchs | Zendy; Joseph R. Carver | Zendy; Susan E. Wiegers | Zendy; Randolph P. Martin | Zendy; Michael H. Picard | Zendy; Robert E. Gerszten | Zendy; Elkan F. Halpern | Zendy; Jonathan Passeri | Zendy; Irene Kuter | Zendy; Marielle ScherrerCrosbie | Zendy

Open Access

Assessment of Echocardiography and Biomarkers for the Extended Prediction of Cardiotoxicity in Patients Treated With Anthracyclines, Taxanes, and Trastuzumab

Author(s) -

Heloisa Sawaya,

Igal A. Sebag,

Juan Carlos Plana,

James L. Januzzi,

Bonnie Ky,

Timothy C. Tan,

Victor Cohen,

José Banchs,

Joseph R. Carver,

Susan E. Wiegers,

Randolph P. Martin,

Michael H. Picard,

Robert E. Gerszten,

Elkan F. Halpern,

Jonathan Passeri,

Irene Kuter,

Marielle ScherrerCrosbie

Publication year - 2012

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.112.973321

Subject(s) - medicine , trastuzumab , cardiotoxicity , ejection fraction , cardiology , natriuretic peptide , heart failure , troponin i , troponin , breast cancer , troponin t , cancer , anthracycline , oncology , chemotherapy , myocardial infarction

Because cancer patients survive longer, the impact of cardiotoxicity associated with the use of cancer treatments escalates. The present study investigates whether early alterations of myocardial strain and blood biomarkers predict incident cardiotoxicity in patients with breast cancer during treatment with anthracyclines, taxanes, and trastuzumab.

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