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Impact of Net Atrioventricular Compliance on Clinical Outcome in Mitral Stenosis
Author(s) -
Maria Carmo Pereira Nunes,
Judy Hung,
Márcia M. Barbosa,
William A. M. Esteves,
Vinícius Tostes Carvalho,
Lucas LodiJunqueira,
Cirilo P. Fonseca Neto,
Timothy C. Tan,
Robert A. Levine
Publication year - 2013
Publication title -
circulation cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.584
H-Index - 99
eISSN - 1942-0080
pISSN - 1941-9651
DOI - 10.1161/circimaging.112.000328
Subject(s) - medicine , cardiology , hazard ratio , prospective cohort study , pulmonary hypertension , stenosis , hemodynamics , asymptomatic , mitral valve , confidence interval , proportional hazards model , doppler echocardiography , blood pressure , diastole
Net atrioventricular compliance (Cn) has been reported to be an important determinant of pulmonary hypertension in mitral stenosis (MS). We hypothesized that it may be useful in assessing prognosis because Cn reflects hemodynamic consequences of MS. To date, limited data with an assumed Cn cutoff have indicated the need for larger prospective studies. This prospective study was designed to determine the impact of Cn on clinical outcome and its contribution to pulmonary pressure in MS. In addition, we aimed to identify a cutoff value of Cn for outcome prediction in this setting.

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