Identification and Assessment of Anderson-Fabry Disease by Cardiovascular Magnetic Resonance Noncontrast Myocardial T1 Mapping | Zendy

Daniel Sado | Zendy; Steven K White | Zendy; Stefan K. Piechnik | Zendy; Sanjay M Banypersad | Zendy; Thomas A. Treibel | Zendy; Gabriella Captur | Zendy; Marianna Fontana | Zendy; Viviana Maestrini | Zendy; Andrew Flett | Zendy; Matthew D. Robson | Zendy; Robin Lachmann | Zendy; Elaine Murphy | Zendy; Atul Mehta | Zendy; Derralynn Hughes | Zendy; Stefan Neubauer | Zendy; Perry Elliott | Zendy; James Moon | Zendy

Open Access

Identification and Assessment of Anderson-Fabry Disease by Cardiovascular Magnetic Resonance Noncontrast Myocardial T1 Mapping

Author(s) -

Daniel Sado,

Steven K White,

Stefan K. Piechnik,

Sanjay M Banypersad,

Thomas A. Treibel,

Gabriella Captur,

Marianna Fontana,

Viviana Maestrini,

Andrew Flett,

Matthew D. Robson,

Robin Lachmann,

Elaine Murphy,

Atul Mehta,

Derralynn Hughes,

Stefan Neubauer,

Perry Elliott,

James Moon

Publication year - 2013

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.112.000070

Subject(s) - medicine , left ventricular hypertrophy , cardiology , magnetic resonance imaging , cardiac amyloidosis , cardiomyopathy , hypertensive heart disease , hypertrophic cardiomyopathy , stenosis , amyloidosis , radiology , heart failure , blood pressure

Anderson-Fabry disease (AFD) is a rare but underdiagnosed intracellular lipid disorder that can cause left ventricular hypertrophy (LVH). Lipid is known to shorten the magnetic resonance imaging parameter T1. We hypothesized that noncontrast T1 mapping by cardiovascular magnetic resonance would provide a novel and useful measure in this disease with potential to detect early cardiac involvement and distinguish AFD LVH from other causes.

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