Early Stem Cell Engraftment Predicts Late Cardiac Functional Recovery | Zendy

Junwei Liu | Zendy; Kazim Narsinh | Zendy; Feng Lan | Zendy; Li Wang | Zendy; Patricia K. Nguyen | Zendy; Shijun Hu | Zendy; Andrew Lee | Zendy; Leng Han | Zendy; Yongquan Gong | Zendy; Mei Huang | Zendy; Divya Nag | Zendy; Jarrett Rosenberg | Zendy; Alexandra Chouldechova | Zendy; Robert C. Robbins | Zendy; Joseph C. Wu | Zendy

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Early Stem Cell Engraftment Predicts Late Cardiac Functional Recovery

Author(s) -

Junwei Liu,

Kazim Narsinh,

Feng Lan,

Li Wang,

Patricia K. Nguyen,

Shijun Hu,

Andrew Lee,

Leng Han,

Yongquan Gong,

Mei Huang,

Divya Nag,

Jarrett Rosenberg,

Alexandra Chouldechova,

Robert C. Robbins,

Joseph C. Wu

Publication year - 2012

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.111.969329

Subject(s) - transplantation , cardiac function curve , myocardial infarction , progenitor cell , stem cell , medicine , positron emission tomography , reporter gene , cardiac magnetic resonance imaging , biology , cardiology , cancer research , pathology , magnetic resonance imaging , heart failure , microbiology and biotechnology , nuclear medicine , gene expression , radiology , gene , biochemistry

Human cardiac progenitor cells have demonstrated great potential for myocardial repair in small and large animals, but robust methods for longitudinal assessment of their engraftment in humans is not yet readily available. In this study, we sought to optimize and evaluate the use of positron emission tomography (PET) reporter gene imaging for monitoring human cardiac progenitor cell (hCPC) transplantation in a mouse model of myocardial infarction.

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