Open AccessSpin-Labeling Magnetic Resonance Imaging Detects Increased Myocardial Blood Flow After Endothelial Cell Transplantation in the Infarcted Heart
Author(s) -
HuaLei Zhang,
Hui Qiao,
Rachel S. Frank,
Bin Huang,
Kathleen J. Propert,
Susan S. Margulies,
Victor A. Ferrari,
Jonathan A. Epstein,
Rong Zhou
Publication year - 2012
Publication title -
circulation cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.584
H-Index - 99
eISSN - 1942-0080
pISSN - 1941-9651
DOI - 10.1161/circimaging.111.966317
Subject(s) - matrigel , transplantation , myocardial infarction , magnetic resonance imaging , intraclass correlation , reproducibility , medicine , ventricle , infarction , blood flow , nuclear medicine , cardiology , chemistry , biomedical engineering , angiogenesis , radiology , chromatography
We quantified absolute myocardial blood flow (MBF) using a spin-labeling MRI (SL-MRI) method after transplantation of endothelial cells (ECs) into the infarcted heart. Our aims were to study the temporal changes in MBF in response to EC transplantation and to compare regional MBF with contractile function (wall motion) and microvascular density.
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