Long-Term Improvement in Postinfarct Left Ventricular Global and Regional Contractile Function Is Mediated by Embryonic Stem Cell–Derived Cardiomyocytes | Zendy

Hui Qiao | Zendy; Hualei Zhang | Zendy; Satoshi Yamanaka | Zendy; Vickas V. Patel | Zendy; Nataliya Petrenko | Zendy; Bin Huang | Zendy; Larry R. Muenz | Zendy; Victor A. Ferrari | Zendy; Kenneth R. Boheler | Zendy; Rong Zhou | Zendy

Open Access

Long-Term Improvement in Postinfarct Left Ventricular Global and Regional Contractile Function Is Mediated by Embryonic Stem Cell–Derived Cardiomyocytes

Author(s) -

Hui Qiao,

Hualei Zhang,

Satoshi Yamanaka,

Vickas V. Patel,

Nataliya Petrenko,

Bin Huang,

Larry R. Muenz,

Victor A. Ferrari,

Kenneth R. Boheler,

Rong Zhou

Publication year - 2010

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.110.957431

Subject(s) - cardiology , myocardial infarction , embryonic stem cell , cardiac function curve , medicine , transplantation , myocyte , stem cell , cardiomyoplasty , infarction , induced pluripotent stem cell , heart failure , microbiology and biotechnology , chemistry , biology , gene , biochemistry

Pluripotent stem cells represent one promising source for cellular cardiomyoplasty. In this study, we used cardiac magnetic resonance to examine the ability of highly enriched cardiomyocytes (CMs) derived from murine embryonic stem cells (ESC) to form grafts and improve contractile function of infarcted rat hearts.

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