Open AccessMolecular Imaging of Atherosclerotic Plaques Targeted to Oxidized LDL Receptor LOX-1 by SPECT/CT and Magnetic Resonance
Author(s) -
Dayuan Li,
Amit R. Patel,
Alexander L. Klibanov,
Christopher M. Kramer,
Mirta Ruiz,
BumYong Kang,
Jawahar L. Mehta,
George Beller,
David K. Glover,
Craig H. Meyer
Publication year - 2010
Publication title -
circulation cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.584
H-Index - 99
eISSN - 1942-0080
pISSN - 1941-9651
DOI - 10.1161/circimaging.109.896654
Subject(s) - medicine , magnetic resonance imaging , in vivo , molecular imaging , ldl receptor , preclinical imaging , pathology , gadolinium , emission computed tomography , positron emission tomography , nuclear medicine , lipoprotein , chemistry , radiology , biology , cholesterol , microbiology and biotechnology , organic chemistry
The oxidized low-density lipoprotein receptor (LDLR) LOX-1 plays a crucial role in atherosclerosis. We sought to detect and assess atherosclerotic plaque in vivo by using single-photon emission computed tomography/computed tomography and magnetic resonance imaging and a molecular probe targeted at LOX-1.
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