Vascular Inflammation in Patients With Impaired Glucose Tolerance and Type 2 Diabetes
Author(s) -
Tae Nyun Kim,
Sungeun Kim,
Sae Jeong Yang,
Hye Jin Yoo,
Ji A Seo,
Sin Gon Kim,
Nan Hee Kim,
Sei Hyun Baik,
Dong Seop Choi,
Kyung Mook Choi
Publication year - 2010
Publication title -
circulation cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.584
H-Index - 99
eISSN - 1942-0080
pISSN - 1941-9651
DOI - 10.1161/circimaging.109.888909
Subject(s) - medicine , impaired glucose tolerance , endocrinology , diabetes mellitus , metabolic syndrome , type 2 diabetes , insulin resistance , inflammation , adiponectin , body mass index , triglyceride , type 2 diabetes mellitus , fluorodeoxyglucose , impaired fasting glucose , vascular disease , pathogenesis , cardiology , cholesterol , positron emission tomography , nuclear medicine
Type 2 diabetes mellitus (T2DM) is associated with an increased risk of atherosclerotic cardiovascular disease. Vascular inflammation is a key factor in both the pathogenesis and outcome of atherosclerosis. (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a promising tool for indentifying and quantifying vascular inflammation within atherosclerotic plaques. This study was designed to examine the vascular inflammation measured using FDG-PET in patients with impaired glucose tolerance and T2DM, in comparison with age- and sex-matched control subjects with normal glucose tolerance.
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