Relationships Among Regional Arterial Inflammation, Calcification, Risk Factors, and Biomarkers
Author(s) -
James H.F. Rudd,
Kelly S. Myers,
Sameer Bansilal,
Josef Macháč,
Mark Woodward,
Valentı́n Fuster,
Michael E. Farkouh,
Zahi A. Fayad
Publication year - 2009
Publication title -
circulation cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.584
H-Index - 99
eISSN - 1942-0080
pISSN - 1941-9651
DOI - 10.1161/circimaging.108.811752
Subject(s) - medicine , inflammation , cardiology , biomarker , calcification , risk factor , pathology , biochemistry , chemistry
Fluorodeoxyglucose positron-emission tomography (FDG PET) imaging of atherosclerosis has been used to quantify plaque inflammation and to measure the effect of plaque-stabilizing drugs. We explored how atherosclerotic plaque inflammation varies across arterial territories and how it relates to arterial calcification. We also tested the hypotheses that the degree of local arterial inflammation measured by PET is correlated with the extent of systemic inflammation and presence of risk factors for vascular disease.
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