Serial Noninvasive In Vivo Positron Emission Tomographic Tracking of Percutaneously Intramyocardially Injected Autologous Porcine Mesenchymal Stem Cells Modified for Transgene Reporter Gene Expression | Zendy

Mariann Gyöngyösi | Zendy; Jerónimo Blanco | Zendy; Teréz Márián | Zendy; Lajos Trón | Zendy; Örs Petneházy | Zendy; Zsolt Petrási | Zendy; Rayyan Hemetsberger | Zendy; Juli R. Bagó | Zendy; Gusztáv Font | Zendy; Imre Pávó | Zendy; István Kertész | Zendy; László Balkay | Zendy; Noémi Pávó | Zendy; Anikó Pósa | Zendy; Miklós Emri | Zendy; László Galuska | Zendy; Dara L. Kraitchman | Zendy; Johann Wojta | Zendy; Kurt Huber | Zendy; Dietmar Glogar | Zendy

Open Access

Serial Noninvasive In Vivo Positron Emission Tomographic Tracking of Percutaneously Intramyocardially Injected Autologous Porcine Mesenchymal Stem Cells Modified for Transgene Reporter Gene Expression

Author(s) -

Mariann Gyöngyösi,

Jerónimo Blanco,

Teréz Márián,

Lajos Trón,

Örs Petneházy,

Zsolt Petrási,

Rayyan Hemetsberger,

Juli R. Bagó,

Gusztáv Font,

Imre Pávó,

István Kertész,

László Balkay,

Noémi Pávó,

Anikó Pósa,

Miklós Emri,

László Galuska,

Dara L. Kraitchman,

Johann Wojta,

Kurt Huber,

Dietmar Glogar

Publication year - 2008

Publication title -

circulation cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.584

H-Index - 99

eISSN - 1942-0080

pISSN - 1941-9651

DOI - 10.1161/circimaging.108.797449

Subject(s) - medicine , in vivo , mesenchymal stem cell , reporter gene , transgene , thymidine kinase , myocardial infarction , positron emission tomography , nuclear medicine , transfection , luciferase , pathology , gene expression , gene , cardiology , immunology , biology , biochemistry , virus , microbiology and biotechnology , herpes simplex virus

Porcine bone marrow-derived mesenchymal stem cells (MSCs) were stably transfected with a lentiviral vector for transgene expression of the trifusion protein renilla luciferase, red fluorescent protein and herpes simplex truncated thymidine kinase (LV-RL-RFP-tTK; positron emission tomography [PET] reporter gene) for in vivo noninvasive tracking of the intramyocardially delivered MSC fate.

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