In Vivo Serial Assessment of Aortic Aneurysm Formation in Apolipoprotein E–Deficient Mice via MRI
Author(s) -
Gregory Turner,
Alan R. Olzinski,
Roberta E. Bernard,
Karpagam Aravindhan,
Heather Karr,
Rosanna C. Mirabile,
Robert N. Willette,
Peter J. Gough,
Beat M. Jucker
Publication year - 2008
Publication title -
circulation cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.584
H-Index - 99
eISSN - 1942-0080
pISSN - 1941-9651
DOI - 10.1161/circimaging.108.787358
Subject(s) - in vivo , medicine , ex vivo , histology , apolipoprotein b , angiotensin ii , abdominal aortic aneurysm , aorta , aortic aneurysm , pathology , aneurysm , surgery , biology , cholesterol , receptor , microbiology and biotechnology
Hyperlipidimic mice administered angiotensin II have been used for the study of abdominal aortic aneurysms (AAAs). The purpose of this study was to examine the use of MRI for studying AAA development and for examining the effects of pharmacological intervention on AAA development in the apolipoprotein E-deficient mouse.
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