Irregular Rhythm Adversely Influences Calcium Handling in Ventricular Myocardium | Zendy

LiangHan Ling | Zendy; Ouda Khammy | Zendy; Melissa Byrne | Zendy; Fatemah Amirahmadi | Zendy; A. Foster | Zendy; Gefeng Li | Zendy; Linda Zhang | Zendy; Cristobal G. dos Remedios | Zendy; Chen Chen | Zendy; David M. Kaye | Zendy

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Irregular Rhythm Adversely Influences Calcium Handling in Ventricular Myocardium

Author(s) -

LiangHan Ling,

Ouda Khammy,

Melissa Byrne,

Fatemah Amirahmadi,

A. Foster,

Gefeng Li,

Linda Zhang,

Cristobal G. dos Remedios,

Chen Chen,

David M. Kaye

Publication year - 2012

Publication title -

circulation heart failure

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.352

H-Index - 104

eISSN - 1941-3297

pISSN - 1941-3289

DOI - 10.1161/circheartfailure.112.968321

Subject(s) - phospholamban , medicine , sinus rhythm , heart failure , atrial fibrillation , calcium , ventricular fibrillation , cardiology , myocyte , endoplasmic reticulum , calcium in biology , endocrinology , context (archaeology) , calsequestrin , ryanodine receptor , chemistry , biology , biochemistry , paleontology

Despite adequate rate control, the combination of atrial fibrillation with heart failure (HF) has been shown, in a number of studies, to hasten HF progression. In this context, we aimed to test the hypothesis that an irregular ventricular rhythm causes an alteration in ventricular cardiomyocyte excitation-contraction coupling which contributes to the progression of HF.

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