Toward Genetics-Driven Early Intervention in Dilated Cardiomyopathy | Zendy

Ray E. Hershberger | Zendy; Daniel D. Kinnamon | Zendy; Ana Morales | Zendy; Julie M. GastierFoster | Zendy; Wylie Burke | Zendy; Deborah J. Bowen | Zendy; Deborah A. Nickerson | Zendy; Michael O. Dorschner | Zendy; Garrie J. Haas | Zendy; William T. Abraham | Zendy; Philip F. Binkley | Zendy; Ayesha Hasan | Zendy; Jennifer Host | Zendy; Brent C. Lampert | Zendy; Sakima A. Smith | Zendy; Gordon S. Huggins | Zendy; David DeNofrio | Zendy; Michael S. Kiernan | Zendy; Daniel Fishbein | Zendy; Richard K. Cheng | Zendy; Todd Dardas | Zendy; Wayne C. Levy | Zendy; Claudius Mahr | Zendy; Sofia Carolina Masri | Zendy; April StempienOtero | Zendy; Stephen S. Gottlieb | Zendy; Matthew T. Wheeler | Zendy; Euan A. Ashley | Zendy; Julia Platt | Zendy; Mark Hofmeyer | Zendy; W.H. Wilson Tang | Zendy; Randall Starling | Zendy; Rocio Moran | Zendy; Anjali Owens | Zendy; Kenneth Marguilies | Zendy; Thomas P. Cappola | Zendy; Lee R. Goldberg | Zendy; Susan C. Brozena | Zendy; J. Eduardo Rame | Zendy; Rhondalyn C. McLean | Zendy; Charles K. Moore | Zendy; Matthew deShazo | Zendy; Robert C. Long | Zendy; Francisco Jimenez Carcamo | Zendy; Hakop Hrachian-Haftevani | Zendy; Barry Trachtenberg | Zendy; G. Ashrith | Zendy; Arvind Bhimarahj | Zendy; Jerry D. Estep | Zendy; Nancy K. Sweitzer | Zendy; Carlos D. Bustamante | Zendy; Gail P. Jarvik | Zendy; Eden R. Martin | Zendy; Heidi L. Rehm | Zendy; Patrice DesvigneNickens | Zendy; James Troendle | Zendy; YiPing Fu | Zendy; Lucia A. Hindorff | Zendy

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Toward Genetics-Driven Early Intervention in Dilated Cardiomyopathy

Author(s) -

Daniel D. Kinnamon,

Ana Morales,

Deborah J. Bowen,

Wylie Burke,

Ray E. Hershberger,

Daniel D. Kinnamon,

Ana Morales,

Julie M. GastierFoster,

Wylie Burke,

Deborah J. Bowen,

Deborah A. Nickerson,

Michael O. Dorschner,

Garrie J. Haas,

William T. Abraham,

Philip F. Binkley,

Ayesha Hasan,

Jennifer Host,

Brent C. Lampert,

Sakima A. Smith,

Gordon S. Huggins,

David DeNofrio,

Michael S. Kiernan,

Daniel Fishbein,

Richard K. Cheng,

Todd Dardas,

Wayne C. Levy,

Claudius Mahr,

Sofia Carolina Masri,

April StempienOtero,

Stephen S. Gottlieb,

Matthew T. Wheeler,

Euan A. Ashley,

Julia Platt,

Mark Hofmeyer,

W.H. Wilson Tang,

Randall Starling,

Rocio Moran,

Anjali Owens,

Kenneth Marguilies,

Thomas P. Cappola,

Lee R. Goldberg,

Susan C. Brozena,

J. Eduardo Rame,

Rhondalyn C. McLean,

Charles K. Moore,

Matthew deShazo,

Robert C. Long,

Francisco Jimenez Carcamo,

Hakop Hrachian-Haftevani,

Barry Trachtenberg,

G. Ashrith,

Arvind Bhimarahj,

Jerry D. Estep,

Nancy K. Sweitzer,

Carlos D. Bustamante,

Gail P. Jarvik,

Eden R. Martin,

Heidi L. Rehm,

Patrice DesvigneNickens,

James Troendle,

YiPing Fu,

Lucia A. Hindorff

Publication year - 2017

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-3268

pISSN - 1942-325X

DOI - 10.1161/circgenetics.117.001826

Subject(s) - medicine , intervention (counseling) , genetic testing , asymptomatic , disease , ethnic group , psychiatry , anthropology , sociology

The cause of idiopathic dilated cardiomyopathy (DCM) is unknown by definition, but its familial subtype is considered to have a genetic component. We hypothesize that most idiopathic DCM, whether familial or nonfamilial, has a genetic basis, in which case a genetics-driven approach to identifying at-risk family members for clinical screening and early intervention could reduce morbidity and mortality.

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