Open AccessFamilial Analysis of Epistatic and Sex-Dependent Association of Genes of the Renin–Angiotensin–Aldosterone System and Blood Pressure
Author(s) -
Katrina J. Scurrah,
Angela Lamantia,
Justine A. Ellis,
Stephen Harrap
Publication year - 2017
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.116.001595
Subject(s) - epistasis , renin–angiotensin system , blood pressure , gene , aldosterone , genetics , medicine , association (psychology) , biology , endocrinology , psychology , psychotherapist
Renin-angiotensin-aldosterone system genes have been inconsistently associated with blood pressure, possibly because of unrecognized influences of sex-dependent genetic effects or gene-gene interactions (epistasis).
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