Clinical Utility of Multimarker Genetic Risk Scores for Prediction of Incident Coronary Heart Disease | Zendy

Carlos Iribarren | Zendy; Meng Lü | Zendy; Eric Jorgenson | Zendy; Manuel E. SotoMartínez | Zendy; Carla Lluís-Ganella | Zendy; Isaac Subirana | Zendy; Eduardo Salas | Zendy; Roberto Elosúa | Zendy

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Clinical Utility of Multimarker Genetic Risk Scores for Prediction of Incident Coronary Heart Disease

Author(s) -

Carlos Iribarren,

Meng Lü,

Eric Jorgenson,

Manuel E. SotoMartínez,

Carla Lluís-Ganella,

Isaac Subirana,

Eduardo Salas,

Roberto Elosúa

Publication year - 2016

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-3268

pISSN - 1942-325X

DOI - 10.1161/circgenetics.116.001522

Subject(s) - hazard ratio , medicine , framingham risk score , confidence interval , cohort , asymptomatic , proportional hazards model , cohort study , demography , cardiology , disease , sociology

We evaluated whether including multilocus genetic risk scores (GRSs) into the Framingham Risk Equation improves the predictive capacity, discrimination, and reclassification of asymptomatic individuals with respect to coronary heart disease (CHD) risk.

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