Socioeconomic Status Interacts with the Genetic Effect of a Chromosome 9p21.3 Common Variant to Influence Coronary Artery Calcification and Incident Coronary Events in the Heinz Nixdorf Recall Study (Risk Factors, Evaluation of Coronary Calcium, and Lifestyle) | Zendy

Börge Schmidt | Zendy; Stefanie Frölich | Zendy; Nico Dragano | Zendy; Mirjam Frank | Zendy; Lewin Eisele | Zendy; Sonali Pechlivanis | Zendy; Andreas J. Forstner | Zendy; Markus M. Nöthen | Zendy; Amir A. Mahabadi | Zendy; Raimund Erbel | Zendy; Susanne Moebus | Zendy; KarlHeinz Jöckel | Zendy

Open Access

Socioeconomic Status Interacts with the Genetic Effect of a Chromosome 9p21.3 Common Variant to Influence Coronary Artery Calcification and Incident Coronary Events in the Heinz Nixdorf Recall Study (Risk Factors, Evaluation of Coronary Calcium, and Lifestyle)

Author(s) -

Börge Schmidt,

Stefanie Frölich,

Nico Dragano,

Mirjam Frank,

Lewin Eisele,

Sonali Pechlivanis,

Andreas J. Forstner,

Markus M. Nöthen,

Amir A. Mahabadi,

Raimund Erbel,

Susanne Moebus,

KarlHeinz Jöckel

Publication year - 2017

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.116.001441

Subject(s) - hazard ratio , confidence interval , medicine , population , proportional hazards model , demography , cohort , environmental health , sociology

Genetic variants of a locus within the chromosome 9p21.3 region are consistently associated with coronary artery disease and coronary artery calcification (CAC). The aim of this study was to examine whether a 9p21.3 common variant interacts with socioeconomic status (SES) to influence CAC and incident coronary events in a population-based cohort.

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