Cardiovascular Risk Factors and Ischemic Heart Disease | Zendy

Roberto Elosúa | Zendy; Carla Lluís-Ganella | Zendy; Isaac Subirana | Zendy; Aki S. Havulinna | Zendy; Kristi Läll | Zendy; Gavin Lucas | Zendy; Sergi Sayols-Baixeras | Zendy; Arto Pietilä | Zendy; Maris Alver | Zendy; Antonio Cabrera de León | Zendy; Mariano Sentı́ | Zendy; David S. Siscovick | Zendy; O. MELLANDER | Zendy; Krista Fischer | Zendy; Veikko Salomaa | Zendy; Jaume Marrugat | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Cardiovascular Risk Factors and Ischemic Heart Disease

Author(s) -

Roberto Elosúa,

Carla Lluís-Ganella,

Isaac Subirana,

Aki S. Havulinna,

Kristi Läll,

Gavin Lucas,

Sergi Sayols-Baixeras,

Arto Pietilä,

Maris Alver,

Antonio Cabrera de León,

Mariano Sentı́,

David S. Siscovick,

O. MELLANDER,

Krista Fischer,

Veikko Salomaa,

Jaume Marrugat

Publication year - 2016

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.115.001255

Subject(s) - disease , cardiology , medicine

Cardiovascular risk factors tend to aggregate. The biological and predictive value of this aggregation is questioned and genetics could shed light on this debate. Our aims were to reappraise the impact of risk factor confluence on ischemic heart disease (IHD) risk by testing whether genetic risk scores (GRSs) associated with these factors interact on an additive or multiplicative scale, and to determine whether these interactions provide additional value for predicting IHD risk.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research