Open AccessNovel 6p21.3 Risk Haplotype Predisposes to Acute Coronary Syndrome
Author(s) -
Juha Sinisalo,
Efthymia Vlachopoulou,
Marja Marchesani,
Johanokelainen,
Mikko I. Mäyränpää,
Jani Lappalainen,
Riitta Paakkanen,
Annika Wennerström,
Krista Salli,
Heikki J. Niemi,
Satu Männistö,
Perttu Salo,
Juhani Junttila,
Markku Eskola,
Kjell Nikus,
T. Petteri Arstila,
Markus Perola,
Heikki Huikuri,
Pekka J. Karhunen,
Petri T. Kovanen,
Aarno Palotie,
Aki S. Havulinna,
Carla Lluís-Ganella,
Jaume Marrugat,
Roberto Elosúa,
Veikko Salomaa,
Markku S. Nieminen,
MarjaLiisa Lokki
Publication year - 2016
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-3268
pISSN - 1942-325X
DOI - 10.1161/circgenetics.115.001226
Subject(s) - haplotype , medicine , acute coronary syndrome , cardiology , genetics , myocardial infarction , biology , allele , gene
The HLA-DRB1*01 allele of the human leukocyte antigen has been associated with acute coronary syndrome. Genome-wide association studies have revealed associations with human leukocyte antigen and non-human leukocyte antigen genes of 3 major histocompatibility complex gene classes but not at allelic level.
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