Susceptibility Loci for Clinical Coronary Artery Disease and Subclinical Coronary Atherosclerosis Throughout the Life-Course
Author(s) -
Elias Salfati,
Shuktika Nandkeolyar,
Stephen P. Fortmann,
Stephen Sidney,
Mark A. Hlatky,
Thomas Quertermous,
Alan S. Go,
Carlos Iribarren,
David M. Herrington,
Benjamin A. Goldstein,
Themistocles L. Assimes
Publication year - 2015
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.114.001071
Subject(s) - medicine , subclinical infection , coronary atherosclerosis , coronary artery disease , cardiology , single nucleotide polymorphism , framingham risk score , quartile , artery , disease , genotype , genetics , biology , confidence interval , gene
Recent genome-wide association studies have identified 49 single nucleotide polymorphisms associated with clinical coronary artery disease. The mechanism by which these loci influence risk remains largely unclear.
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