Open AccessContribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry
Author(s) -
Carole Proust,
JeanPhilippe Empana,
Pierre Boutouyrie,
Maureen Alivon,
Pascal Challande,
Nicolas Danchin,
Guillaume Escriou,
Ulrike Esslinger,
Stéphane Laurent,
Zhenlin Li,
Bruno Pannier,
Véronique Regnault,
Frédérique Thomas,
Xavier Jouven,
François Cambien,
Patrick Lacolley
Publication year - 2015
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.114.000979
Subject(s) - heritability , arterial stiffness , minor allele frequency , common carotid artery , medicine , genetic association , genome wide association study , cholesterol , genetics , gene , allele frequency , allele , biology , genotype , single nucleotide polymorphism , blood pressure , carotid arteries
We assess the contribution of common and rare putatively functional genetic variants (most of them coding) present on the Illumina exome Beadchip to the variability of plasma lipids and stiffness of the common carotid artery.
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