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Association of Rare Loss-Of-Function Alleles in HAL , Serum Histidine
Author(s) -
Bing Yu,
Alexander Li,
Donna M. Muzny,
Narayanan Veeraraghavan,
Paul S. de Vries,
Joshua C. Bis,
Solomon K. Musani,
Danny Alexander,
Alanna C. Morrison,
Oscar H. Franco,
André G. Uitterlinden,
Albert Hofman,
Abbas Dehghan,
James G. Wilson,
Bruce M. Psaty,
Richard A. Gibbs,
Peng Wei,
Eric Boerwinkle
Publication year - 2015
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.114.000697
Subject(s) - histidine , genotyping , minor allele frequency , allele , population , medicine , genetics , allele frequency , biology , gene , genotype , amino acid , environmental health
Histidine is a semiessential amino acid with antioxidant and anti-inflammatory properties. Few data are available on the associations between genetic variants, histidine levels, and incident coronary heart disease (CHD) in a population-based sample.

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