Genetic Evidence for PLASMINOGEN as a Shared Genetic Risk Factor of Coronary Artery Disease and Periodontitis
Author(s) -
Arne S. Schäefer,
Gregor Bochenek,
Arne Jochens,
David Ellinghaus,
Henrik Dommisch,
Esra Güzeldemir,
Christian Graetz,
Inga Harks,
Yvonne JockelSchneider,
Knut Weinspach,
Joerg Meyle,
Peter Eickholz,
Gerard J. Linden,
Naci Çine,
Rahime M. Nohutçu,
Ervin I. Weiss,
Yael HouriHaddad,
Fuad A. Iraqi,
Mathias Folwaczny,
Barbara Noack,
Konstantin Strauch,
Christian Gieger,
Mélanie Waldenberger,
Annette Peters,
Cisca Wijmenga,
Engin Yılmaz,
Wolfgang Lieb,
Philip Rosenstiel,
Christof Doerfer,
Corinna Bruckmann,
Jeanette Erdmann,
Inke R. König,
Søren Jepsen,
Bruno G. Loos,
Stefan Schreiber
Publication year - 2014
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.114.000554
Subject(s) - odds ratio , periodontitis , genome wide association study , genetics , case control study , biology , risk factor , coronary artery disease , allele , confidence interval , bioinformatics , medicine , oncology , genotype , single nucleotide polymorphism , gene
Genetic studies demonstrated the presence of risk alleles in the genes ANRIL and CAMTA1/VAMP3 that are shared between coronary artery disease (CAD) and periodontitis. We aimed to identify further shared genetic risk factors to better understand conjoint disease mechanisms.
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