Identification of Genetic Markers for Treatment Success in Heart Failure Patients | Zendy

Boris Schmitz | Zendy; Renata De Maria | Zendy; Dimitrios Gatsios | Zendy; Theodora Chrysanthakopoulou | Zendy; Maurizio Landolina | Zendy; Maurizio Gasparini | Zendy; Jonica Campolo | Zendy; Marina Parolini | Zendy; Antonio Sanzo | Zendy; Paola Galimberti | Zendy; Michele Leonardo Bianchi | Zendy; Malte Lenders | Zendy; Eva Brand | Zendy; Oberdan Parodi | Zendy; Maurizio Lunati | Zendy; Stefan-Martin Brand | Zendy

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Identification of Genetic Markers for Treatment Success in Heart Failure Patients

Author(s) -

Boris Schmitz,

Renata De Maria,

Dimitrios Gatsios,

Theodora Chrysanthakopoulou,

Maurizio Landolina,

Maurizio Gasparini,

Jonica Campolo,

Marina Parolini,

Antonio Sanzo,

Paola Galimberti,

Michele Leonardo Bianchi,

Malte Lenders,

Eva Brand,

Oberdan Parodi,

Maurizio Lunati,

Stefan-Martin Brand

Publication year - 2014

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.113.000384

Subject(s) - heart failure , identification (biology) , genetic marker , medicine , genetics , bioinformatics , computational biology , biology , gene , botany

Cardiac resynchronization therapy (CRT) can improve ventricular size, shape, and mass and reduce mitral regurgitation by reverse remodeling of the failing ventricle. About 30% of patients do not respond to this therapy for unknown reasons. In this study, we aimed at the identification and classification of CRT responder by the use of genetic variants and clinical parameters.

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