Genome-Wide Association Study of Plasma N6 Polyunsaturated Fatty Acids Within the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium | Zendy

Weihua Guan | Zendy; Brian T. Steffen | Zendy; Rozenn N. Lemaître | Zendy; Jason Wu | Zendy; Toshiko Tanaka | Zendy; Ani Manichaikul | Zendy; Millennia Foy | Zendy; Stephen S. Rich | Zendy; Lu Wang | Zendy; Jennifer A. Nettleton | Zendy; Weihong Tang | Zendy; Xiangjun Gu | Zendy; Stafania Bandinelli | Zendy; Irena B. King | Zendy; Barbara McKnight | Zendy; Bruce M. Psaty | Zendy; David S. Siscovick | Zendy; Luc Djoussé | Zendy; Yii-Der Ida Chen | Zendy; Luigi Ferrucci | Zendy; Myriam Fornage | Zendy; Dariush Mozafarrian | Zendy; Michael Y. Tsai | Zendy; Lyn M. Steffen | Zendy

Open Access

Genome-Wide Association Study of Plasma N6 Polyunsaturated Fatty Acids Within the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

Author(s) -

Weihua Guan,

Brian T. Steffen,

Rozenn N. Lemaître,

Jason Wu,

Toshiko Tanaka,

Ani Manichaikul,

Millennia Foy,

Stephen S. Rich,

Lu Wang,

Jennifer A. Nettleton,

Weihong Tang,

Xiangjun Gu,

Stafania Bandinelli,

Irena B. King,

Barbara McKnight,

Bruce M. Psaty,

David S. Siscovick,

Luc Djoussé,

Yii-Der Ida Chen,

Luigi Ferrucci,

Myriam Fornage,

Dariush Mozafarrian,

Michael Y. Tsai,

Lyn M. Steffen

Publication year - 2014

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.113.000208

Subject(s) - polyunsaturated fatty acid , genome wide association study , biology , genetic epidemiology , genetics , gene , fatty acid , bioinformatics , biochemistry , genotype , single nucleotide polymorphism

Omega6 (n6) polyunsaturated fatty acids (PUFAs) and their metabolites are involved in cell signaling, inflammation, clot formation, and other crucial biological processes. Genetic components, such as variants of fatty acid desaturase (FADS) genes, determine the composition of n6 PUFAs.

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