Coronary Heart Disease in Systemic Lupus Erythematosus Is Associated With Interferon Regulatory Factor-8 Gene Variants
Author(s) -
Dag Leonard,
Elisabet Svenungsson,
Johanna K. Sandling,
Olof Berggren,
Andreas Jönsen,
Christine Bengtsson,
Chuan Wang,
Kerstin JensenUrstad,
Sven-Olof Granstam,
Anders Bengtsson,
Johanna Gustafsson,
Iva Gunnarsson,
Solbritt RantapääDahlqvist,
Gunnel Nordmark,
MaijaLeena Eloranta,
AnnChristine Syvänen,
Lars Rönnblom
Publication year - 2013
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.113.000044
Subject(s) - single nucleotide polymorphism , allele , linkage disequilibrium , risk factor , immunology , medicine , snp , allele frequency , odds ratio , population , minor allele frequency , genetics , biology , genotype , gene , environmental health
Patients with systemic lupus erythematosus have increased morbidity and mortality in coronary heart disease (CHD). We asked whether there was a genetic influence on CHD in systemic lupus erythematosus.
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