Association of Genome-Wide Variation With Highly Sensitive Cardiac Troponin-T Levels in European Americans and Blacks | Zendy

Bing Yu | Zendy; Maja Barbalić | Zendy; Ariel Brautbar | Zendy; Vijay Nambi | Zendy; Ron C. Hoogeveen | Zendy; Weihong Tang | Zendy; Thomas H. Mosley | Zendy; Jerome I. Rotter | Zendy; Christopher R. deFilippi | Zendy; Christopher J. O’Donnell | Zendy; Sekar Kathiresan | Zendy; Kenneth Rice | Zendy; Susan R. Heckbert | Zendy; Christie M. Ballantyne | Zendy; Bruce M. Psaty | Zendy; Eric Boerwinkle | Zendy

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Association of Genome-Wide Variation With Highly Sensitive Cardiac Troponin-T Levels in European Americans and Blacks

Author(s) -

Bing Yu,

Maja Barbalić,

Ariel Brautbar,

Vijay Nambi,

Ron C. Hoogeveen,

Weihong Tang,

Thomas H. Mosley,

Jerome I. Rotter,

Christopher R. deFilippi,

Christopher J. O’Donnell,

Sekar Kathiresan,

Kenneth Rice,

Susan R. Heckbert,

Christie M. Ballantyne,

Bruce M. Psaty,

Eric Boerwinkle

Publication year - 2012

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.112.963058

Subject(s) - medicine , hazard ratio , troponin t , genome wide association study , heart failure , cardiology , single nucleotide polymorphism , biology , genetics , confidence interval , genotype , gene , myocardial infarction

High levels of cardiac troponin T, measured by a highly sensitive assay (hs-cTnT), are strongly associated with incident coronary heart disease and heart failure. To date, no large-scale genome-wide association study of hs-cTnT has been reported. We sought to identify novel genetic variants that are associated with hs-cTnT levels.

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