Associations Between Incident Ischemic Stroke Events and Stroke and Cardiovascular Disease-Related Genome-Wide Association Studies Single Nucleotide Polymorphisms in the Population Architecture Using Genomics and Epidemiology Study
Author(s) -
Cara L. Carty,
Petra Bůžková,
Myriam Fornage,
Nora Franceschini,
Shelley A. Cole,
Gerardo Heiss,
Lucia A. Hindorff,
Barbara V. Howard,
Sue Mann,
Lisa W. Martin,
Ying Zhang,
Tara C. Matise,
Ross L. Prentice,
Alexander P. Reiner,
Charles Kooperberg
Publication year - 2012
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.111.962191
Subject(s) - genome wide association study , single nucleotide polymorphism , genetic association , stroke (engine) , hazard ratio , medicine , population , genetic epidemiology , mendelian randomization , epidemiology , genetics , biology , bioinformatics , genotype , genetic variants , environmental health , confidence interval , mechanical engineering , gene , engineering
Genome-wide association studies (GWAS) have identified loci associated with ischemic stroke (IS) and cardiovascular disease (CVD) in European-descent individuals, but their replication in different populations has been largely unexplored.
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