Association of Variation at the ABO Locus With Circulating Levels of Soluble Intercellular Adhesion Molecule-1, Soluble P-selectin, and Soluble E-selectin
Author(s) -
Stefan Kiechl,
Guillaume Paré,
Maja Barbalić,
Lu Qi,
Josée Dupuis,
Abbas Dehghan,
Joshua C. Bis,
Ross C. Laxton,
Qingzhong Xiao,
Enzo Bonora,
Johann Willeit,
Qingbo Xu,
Jacqueline C.M. Witteman,
Daniel I. Chasman,
Russell P. Tracy,
Christie M. Ballantyne,
Paul M. Ridker,
Emelia J. Benjamin,
Shu Ye
Publication year - 2011
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.111.960682
Subject(s) - allele , abo blood group system , locus (genetics) , heterozygote advantage , intercellular adhesion molecule 1 , e selectin , biology , intracellular , microbiology and biotechnology , chemistry , genetics , medicine , cell adhesion , gene , cell
Circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin have been associated with variation at the ABO locus. To evaluate these associations and the effect sizes, we performed a meta-analysis with new and previous reported data for polymorphism rs579459.
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