Selective MicroRNA Suppression in Human Thoracic Aneurysms | Zendy

Jeffrey A. Jones | Zendy; Robert E. Stroud | Zendy; Elizabeth C. O’Quinn | Zendy; L. Black | Zendy; Jeremy L. Barth | Zendy; John A. Elefteriades | Zendy; Joseph E. Bavaria | Zendy; Joseph H. Gorman | Zendy; Robert C. Gorman | Zendy; Francis G. Spinale | Zendy; John S. Ikonomidis | Zendy

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Selective MicroRNA Suppression in Human Thoracic Aneurysms

Author(s) -

Jeffrey A. Jones,

Robert E. Stroud,

Elizabeth C. O’Quinn,

L. Black,

Jeremy L. Barth,

John A. Elefteriades,

Joseph E. Bavaria,

Joseph H. Gorman,

Robert C. Gorman,

Francis G. Spinale,

John S. Ikonomidis

Publication year - 2011

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.111.960419

Subject(s) - microrna , medicine , biology , bioinformatics , computational biology , gene , genetics

Increasing evidence points to a direct role for altered microRNA (miRNA or miR) expression levels in cardiovascular remodeling and disease progression. Although alterations in miR expression levels have been directly linked to cardiac hypertrophy, fibrosis, and remodeling, their role in regulating gene expression during thoracic aortic aneurysm (TAA) development has yet to be explored.

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