Genomic Risk Variants at 1p13.3, 1q41, and 3q22.3 Are Associated With Subsequent Cardiovascular Outcomes in Healthy Controls and in Established Coronary Artery Disease | Zendy

Katrina L. Ellis | Zendy; Chris Frampton | Zendy; Anna P. Pilbrow | Zendy; Richard W. Troughton | Zendy; Robert N. Doughty | Zendy; Gillian Whalley | Zendy; Chris Ellis | Zendy; Lorraine Skelton | Zendy; Judith Thomson | Zendy; Timothy G. Yandle | Zendy; Mark Richards | Zendy; Vicky A. Cameron | Zendy

Open Access

Genomic Risk Variants at 1p13.3, 1q41, and 3q22.3 Are Associated With Subsequent Cardiovascular Outcomes in Healthy Controls and in Established Coronary Artery Disease

Author(s) -

Katrina L. Ellis,

Chris Frampton,

Anna P. Pilbrow,

Richard W. Troughton,

Robert N. Doughty,

Gillian Whalley,

Chris Ellis,

Lorraine Skelton,

Judith Thomson,

Timothy G. Yandle,

Mark Richards,

Vicky A. Cameron

Publication year - 2011

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.111.960336

Subject(s) - medicine , coronary artery disease , myocardial infarction , dyslipidemia , cardiology , family history , cohort , disease

Genome-wide association studies have identified gene variants associated with coronary artery disease risk; however, whether they affect disease progression is largely unknown. This study investigated associations between polymorphisms at 1p13.3 (rs599839), 1q41 (rs17465637), and 3q22.3 (rs9818870) and cardiovascular outcomes in healthy volunteers and in patients with established heart disease.

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