Four Genetic Loci Influencing Electrocardiographic Indices of Left Ventricular Hypertrophy
Author(s) -
Sonia Shah,
Christopher P. Nelson,
Tom R. Gaunt,
Pim van der Harst,
Timothy Barnes,
Peter S. Braund,
Debbie A. Lawlor,
Juan-Pablo Casas,
Sandosh Padmanabhan,
Fotios Drenos,
Mika Kivimäki,
Philippa J. Talmud,
Steve E. Humphries,
John C. Whittaker,
Richard Morris,
Peter H. Whincup,
Anna F. Dominiczak,
Patricia B. Munroe,
Toby Johnson,
Alison H. Goodall,
François Cambien,
Patrick Diemert,
Christian Hengstenberg,
Willem H. Ouwehand,
Janine F. Felix,
Nicole L. Glazer,
Maciej Tomaszewski,
Paul R. Burton,
Martin D. Tobin,
Dirk J. van Veldhuisen,
Rudolf A. de Boer,
Gerjan Navis,
Wiek H. van Gilst,
Bongani M. Mayosi,
John R. Thompson,
Meena Kumari,
Peter W. Macfarlane,
Ian N.M. Day,
Aroon D. Hingorani,
Nilesh J. Samani
Publication year - 2011
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.111.960203
Subject(s) - left ventricular hypertrophy , cardiology , medicine , blood pressure
Presence of left ventricular hypertrophy on an ECG (ECG-LVH) is widely assessed clinically and provides prognostic information in some settings. There is evidence for significant heritability of ECG-LVH. We conducted a large-scale gene-centric association analysis of 4 commonly measured indices of ECG-LVH.
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