Association of Genetic Variants and Incident Coronary Heart Disease in Multiethnic Cohorts
Author(s) -
Nora Franceschini,
Cara L. Carty,
Petra Bůžková,
Alex P. Reiner,
Tiana A. Garrett,
Yi Lin,
Jens-S. Vöckler,
Lucia A. Hindorff,
Shelley A. Cole,
Eric Boerwinkle,
D. Y. Lin,
Ebony Bookman,
Lyle G. Best,
Jonathan N. Bella,
Charles B. Eaton,
Philip Greenland,
Nancy S. Jenny,
Kari E. North,
Darin Taverna,
Alicia Young,
Ewa Deelman,
Charles Kooperberg,
Bruce M. Psaty,
Gerardo Heiss
Publication year - 2011
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.111.960096
Subject(s) - coronary heart disease , medicine , association (psychology) , genome wide association study , disease , genetic variants , cardiology , demography , genetics , single nucleotide polymorphism , genotype , biology , psychology , gene , psychotherapist , sociology
Genome-wide association studies identified several single nucleotide polymorphisms (SNP) associated with prevalent coronary heart disease (CHD), but less is known of associations with incident CHD. The association of 13 published CHD SNPs was examined in 5 ancestry groups of 4 large US prospective cohorts.
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