Differential MicroRNA Expression Profiles in Peripheral Arterial Disease | Zendy

Philip Stather | Zendy; Nicolas Sylvius | Zendy; Philipp S. Wild | Zendy; Edward Choke | Zendy; Shu Ye | Zendy; Matthew J. Bown | Zendy

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Differential MicroRNA Expression Profiles in Peripheral Arterial Disease

Author(s) -

Philip Stather,

Nicolas Sylvius,

Philipp S. Wild,

Edward Choke,

Shu Ye,

Matthew J. Bown

Publication year - 2013

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.111.000053

Subject(s) - microrna , transcriptome , arterial disease , gene expression profiling , gene expression , biology , gene , biological pathway , peripheral , computational biology , bioinformatics , fold change , vascular disease , medicine , genetics

Peripheral arterial disease (PAD) is a clinical condition caused by an atherosclerotic process affecting the arteries of the limbs. Despite major improvements in surgical endovascular techniques, PAD is still associated with high mortality and morbidity. Recently, microRNAs (miRNAs), a class of short noncoding RNA controlling gene expression, have emerged as major regulators of multiple biological processes.

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