Genome-Wide Significance and Replication of the Chromosome 12p11.22 Locus Near the PTHLH Gene for Peripartum Cardiomyopathy | Zendy

Benjamin D. Horne | Zendy; Kismet Rasmusson | Zendy; Rami Alharethi | Zendy; D. Budge | Zendy; Kimberly D. Brunisholz | Zendy; Torri D. Metz | Zendy; John F. Carlquist | Zendy; Jennifer J. Connolly | Zendy; T. Flint Porter | Zendy; Donald Lappé | Zendy; Joseph B. Muhlestein | Zendy; Robert Silver | Zendy; Josef Stehlik | Zendy; Namje Park | Zendy; Heidi T. May | Zendy; Tami L. Bair | Zendy; Jeffrey L. Anderson | Zendy; Dale G. Renlund | Zendy; Abdallah G. Kfoury | Zendy

Open Access

Genome-Wide Significance and Replication of the Chromosome 12p11.22 Locus Near the PTHLH Gene for Peripartum Cardiomyopathy

Author(s) -

Benjamin D. Horne,

Kismet Rasmusson,

Rami Alharethi,

D. Budge,

Kimberly D. Brunisholz,

Torri D. Metz,

John F. Carlquist,

Jennifer J. Connolly,

T. Flint Porter,

Donald Lappé,

Joseph B. Muhlestein,

Robert Silver,

Josef Stehlik,

Namje Park,

Heidi T. May,

Tami L. Bair,

Jeffrey L. Anderson,

Dale G. Renlund,

Abdallah G. Kfoury

Publication year - 2011

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.110.959205

Subject(s) - peripartum cardiomyopathy , locus (genetics) , genetics , genome , chromosome , cardiomyopathy , biology , gene , medicine , cardiology , heart failure

Peripartum (PP) cardiomyopathy (CM) is a rare condition of unknown etiology that occurs in late pregnancy or early postpartum. Initial evidence suggests that genetic factors may influence PPCM. This study evaluated and replicated genome-wide association of single nucleotide polymorphisms with PPCM.

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