Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage | Zendy

Yasuhide Kuwabara | Zendy; Koh Ono | Zendy; Takahiro Horie | Zendy; Hitoo Nishi | Zendy; Kazuya Nagao | Zendy; Minako Kinoshita | Zendy; Shin Watanabe | Zendy; Osamu Baba | Zendy; Yoji Kojima | Zendy; Satoshi Shizuta | Zendy; Masao Imai | Zendy; Toshihiro Tamura | Zendy; Toru Kita | Zendy; Takeshi Kimura | Zendy

Open Access

Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage

Author(s) -

Yasuhide Kuwabara,

Koh Ono,

Takahiro Horie,

Hitoo Nishi,

Kazuya Nagao,

Minako Kinoshita,

Shin Watanabe,

Osamu Baba,

Yoji Kojima,

Satoshi Shizuta,

Masao Imai,

Toshihiro Tamura,

Toru Kita,

Takeshi Kimura

Publication year - 2011

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.110.958975

Subject(s) - microrna , disease , medicine , cardiology , biology , genetics , gene

Recently, elevation of circulating muscle-specific microRNA (miRNA) levels has been reported in patients with acute myocardial infarction. However, it is still unclear from which part of the myocardium or under what conditions miRNAs are released into circulating blood. The purpose of this study was to identify the source of elevated levels of circulating miRNAs and their function in cardiovascular diseases.

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