Common Variants in Epithelial Sodium Channel Genes Contribute to Salt Sensitivity of Blood Pressure | Zendy

Qi Zhao | Zendy; Dongfeng Gu | Zendy; James E. Hixson | Zendy; DePei Liu | Zendy; D. C. Rao | Zendy; Cashell E. Jaquish | Zendy; Tanika N. Kelly | Zendy; Fanghong Lu | Zendy; Jixiang Ma | Zendy; Jianjun Mu | Zendy; Lawrence C. Shimmin | Zendy; Jichun Chen | Zendy; Hao Mei | Zendy; L. Lee Hamm | Zendy; Jiang He | Zendy

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Common Variants in Epithelial Sodium Channel Genes Contribute to Salt Sensitivity of Blood Pressure

Author(s) -

Qi Zhao,

Dongfeng Gu,

James E. Hixson,

DePei Liu,

D. C. Rao,

Cashell E. Jaquish,

Tanika N. Kelly,

Fanghong Lu,

Jixiang Ma,

Jianjun Mu,

Lawrence C. Shimmin,

Jichun Chen,

Hao Mei,

L. Lee Hamm,

Jiang He

Publication year - 2011

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.110.958629

Subject(s) - epithelial sodium channel , sodium , blood pressure , single nucleotide polymorphism , medicine , allele , endocrinology , population , snp , sodium channel , physiology , genetics , gene , genotype , biology , chemistry , environmental health , organic chemistry

Rare mutations of the epithelial sodium channel (ENaC) lead to mendelian forms of salt-sensitive hypertension or salt-wasting hypotension. We aimed to examine the association between common variants in the ENaC genes and salt sensitivity of blood pressure (BP).

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