Familial Thoracic Aortic Aneurysms and Dissections | Zendy

Dong-Chuan Guo | Zendy; Ellen S. Regalado | Zendy; Charles Minn | Zendy; Van TranFadulu | Zendy; Joshua Coney | Zendy; Jiumei Cao | Zendy; Min Wang | Zendy; Robert Yu | Zendy; Anthony L. Estrera | Zendy; Hazim J. Safi | Zendy; Sanjay Shete | Zendy; Dianna M. Milewicz | Zendy

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Familial Thoracic Aortic Aneurysms and Dissections

Author(s) -

Dong-Chuan Guo,

Ellen S. Regalado,

Charles Minn,

Van TranFadulu,

Joshua Coney,

Jiumei Cao,

Min Wang,

Robert Yu,

Anthony L. Estrera,

Hazim J. Safi,

Sanjay Shete,

Dianna M. Milewicz

Publication year - 2010

Publication title -

circulation cardiovascular genetics

Language(s) - English

Resource type - Journals

eISSN - 1942-325X

pISSN - 1942-3268

DOI - 10.1161/circgenetics.110.958066

Subject(s) - aortic dissection , medicine , penetrance , thoracic aortic aneurysm , ascending aorta , aortic aneurysm , locus (genetics) , aneurysm , thoracic aorta , cardiology , family history , aorta , dissection (medical) , surgery , genetics , gene , biology , phenotype

Thoracic aortic aneurysms leading to acute aortic dissections are the major diseases that affect the thoracic aorta. Approximately 20% of patients with thoracic aortic aneurysms and dissections (TAAD) have a family history of TAAD, and these patients present younger with more rapidly enlarging aneurysms than patients without a family history of aortic disease.

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