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Ancestry as a Determinant of Mean Population C-Reactive Protein Values
Author(s) -
Tina Shah,
Paul J. Newcombe,
Liam Smeeth,
Juliet Addo,
Juan P. Casas,
John C. Whittaker,
Michelle A. Miller,
Lorna Tinworth,
Steve Jeffery,
Pasquale Strazzullo,
Francesco P. Cappuccio,
Aroon D. Hingorani
Publication year - 2010
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.110.957431
Subject(s) - population , genetics , biology , demography , medicine , environmental health , sociology
Eligibility for rosuvastatin treatment for cardiovascular disease prevention includes a C-reactive protein (CRP) concentration >2 mg/L. Most observational studies of CRP and cardiovascular disease have been in Europeans. We evaluated the influence of ancestry on population CRP concentration to assess the implications for statin targeting in non-Europeans.

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