Quantitative Trait Locus Mapping and Identification of Zhx2 as a Novel Regulator of Plasma Lipid Metabolism
Author(s) -
Peter S. Gargalovic,
Ayça Erbilgin,
Omid Kohannim,
Joanne Pag,
Xuping Wang,
Lawrence W. Castellani,
Renee Leboeuf,
Martha L. Peterson,
Brett T. Spear,
Aldons J. Lusis
Publication year - 2009
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.109.902320
Subject(s) - biology , locus (genetics) , quantitative trait locus , gene , genetics , regulator , congenic , transgene , ectopic expression , lipid metabolism , complementation , phenotype , biochemistry
We previously mapped a quantitative trait locus on chromosome 15 in mice contributing to high-density lipoprotein cholesterol and triglyceride levels and now report the identification of the underlying gene.
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